1528 Locust street, Downtown St. Louis, Saint Louis, 63103, United States
Preferred Partner
Boutique
About the Hotel
7.9Average Rating
Nestled in the heart of Saint Louis, the 21c Museum Hotel St Louis offers a unique blend of contemporary art and luxurious accommodation that will captivate even the most discerning traveler. This four-star gem seamlessly marries the worlds of hospitality and culture, inviting guests to immerse themselves in a curated experience that extends far beyond the typical hotel stay. As you step into the lobby, you're immediately enveloped by an atmosphere of refined creativity, setting the tone for a truly memorable sojourn.
The hotel's wellness offerings are nothing short of exceptional, featuring a serene indoor swimming pool, a state-of-the-art spa, and a rejuvenating hot tub. Indulge in a personalized massage or partake in one of the invigorating yoga classes, followed by a detoxifying session in the steam room or sauna. For those who prefer to maintain their fitness regimen while traveling, the well-equipped fitness center is at your disposal. As the day winds down, retreat to your thoughtfully appointed room, where modern amenities like streaming services and spacious work desks blend seamlessly with luxurious touches such as plush bathrobes and bespoke toiletries.
Culinary enthusiasts will delight in the hotel's modern restaurant, which serves up innovative Spanish cuisine in an ambiance that's both sophisticated and welcoming. After dinner, the stylish bar beckons, offering the perfect setting to unwind with a carefully crafted cocktail. For those traveling with furry companions, the 21c Museum Hotel St Louis extends a warm welcome to pets, ensuring that no family member is left behind. With its prime location in Saint Louis' city center, just a stone's throw from iconic attractions like the Old Courthouse and Laclede's Landing, this hotel isn't just a place to stay – it's a destination in itself, promising an artful escape in the heart of the city.
Accommodations
15 Types Available
Deluxe King Suite
264 m²
2
Bunk Room
264 m²
2
Deluxe King Room
309 m²
2
Deluxe King Room - Accessible
309 m²
2
Corner King Room
326 m²
2
Deluxe Room with Two Queen Beds - Accessible
366 m²
4
Deluxe Double Queen Room with Roll-In Shower
366 m²
4
Deluxe Queen Room
369 m²
4
Luxury Queen Room
423 m²
4
Loft with Two Queen Beds
433 m²
4
Corner King Suite
475 m²
2
Deluxe King Suite with Roll-In Shower - Accessible
506 m²
2
Luxury King Suite
549 m²
2
Luxury King Suite
549 m²
2
Library King Suite
732 m²
2
Amenities
Very good breakfast
Private
Indoor swimming pool
Spa
Hot tub/Jacuzzi
Massage
Pets welcome
Fees may apply
Refrigerator
Common Questions
21c Museum Hotel St Louis combines a contemporary art museum with a boutique hotel experience. It offers rotating art exhibitions throughout public spaces, an indoor swimming pool, spa services, and a restaurant serving Spanish cuisine. The hotel's prime location in downtown St. Louis also puts guests close to major attractions.
Yes, the hotel features an indoor swimming pool. Guests can also enjoy other wellness amenities including a spa, hot tub, sauna, and steam room.
The hotel has a modern restaurant that serves Spanish cuisine for dinner. There's also a bar that provides a relaxing atmosphere for evening drinks. Additionally, the hotel is known for its very good breakfast offerings.
The hotel is located approximately 13 miles from St. Louis Lambert International Airport. It's situated in the city center, providing convenient access to both the airport and local attractions.
Yes, pets are welcome at the hotel. However, please note that fees may apply for bringing your pet. It's best to contact the hotel directly for specific pet policies and any associated costs.
Rooms at 21c Museum Hotel St Louis feature air-conditioning, private bathrooms, bathrobes, and free toiletries. They also come equipped with streaming services, work desks, seating areas, and refrigerators for guest convenience.
Yes, the hotel offers yoga and fitness classes for guests. There's also a fitness room available for those who prefer to work out on their own.
The hotel is conveniently located near several attractions. Old Courthouse, Laclede's Landing, and Edward Jones Dome are each about 1.2 miles away from the property.
Yes, 21c Museum Hotel St Louis offers several accessible room options. These include the Deluxe King Room - Accessible, Deluxe Room with Two Queen Beds - Accessible, Deluxe Double Queen Room with Roll-In Shower, and Deluxe King Suite with Roll-In Shower - Accessible.
The hotel features a spa and wellness center that offers massage services. Guests can also enjoy other relaxation amenities such as a hot tub, sauna, and steam room. For specific treatments and services, it's recommended to contact the hotel directly.
21c Museum Hotel St Louis breakfast is offered on certain rates. However, when you book through First Row travel we can offer you special partner rates with breakfast included, amongst other benefits.
21c Museum Hotel St Louis is a partner of First Row Travel. When you book an eligible rate through us, you'll get a room upgrade subject to availability at time of check-in : no status with the chain needed
Late checkout or early check-in can be provided at 21c Museum Hotel St Louis for an additional cost. However, when you book an eligible rate through First Row Travel you get complimentary early check-in/late check-out subject to availability
Experience unparalleled luxury at the 5-star Four Seasons St. Louis, boasting city and Gateway Arch views, a rooftop pool, spa, and fine Italian dining at Cielo Restaurant, all steps from downtown attractions.
This sophisticated 4-star hotel in downtown St. Louis blends art and luxury, offering a spa, indoor pool, and Spanish cuisine, while nestled near iconic attractions like the Old Courthouse.
We're not just a booking engine — we're seasoned travelers. From your first inquiry to your safe return, we're your dedicated travel team. Whether you need end-to-end planning, specific recommendations, or just a VIP reservation, we're here to elevate your journey.